What is Ledifos (Ledipasvir/Sofosbuvir) used for?

Ledifos is a combination antiviral agent containing 90mg of Ledipasvir and 400mg of Sofosbuvir in each tablet. It will help prevent the spread of hepatitis C virus (HCV) and is a recommended treatment for people suffering from hepatitis C, particularly of the genotype 1.

How should I use Ledifos (Ledipasvir/Sofosbuvir)?

Dosage instructions will be provided to you by your doctor. Follow this, and any other advice they give you very carefully.

Ledifos should only be taken as prescribed by your doctor and is only suitable for use by adults with chronic hepatitis C. The dosage will depend on the patient and the severity of the condition, however the same dosage will usually be taken daily. Tablets should be swallowed whole with a glass of water and can be taken with or without food.

What are the side effects of Ledifos (Ledipasvir/Sofosbuvir)?

Ledifos has a minimal side effect profile, and can be used by the majority of patients with no ill effects.

The most common side effects of Ledifos are headaches, tiredness, loss of appetite, diarrhea, lower back pain. If you notice any of these and they are a bother to you, contact your doctor.

If you see any signs that you may be allergic to Ledifos (eg. rash, hives, excessive itching, unusual difficulty breathing, tightness in your chest, or swelling of the mouth, face, lips, or tongue) seek medical attention immediately and stop taking Ledifos.

Please Note

Ledifos (Ledipasvir/Sofobuvir) is a good choice of treatment for many people with hepatitis C, however it is not for everybody. People in any of the following situations should not take Ledifos.

• if have an allergy to the active ingredients (ledipasvir or sofosbuvir)
• if you are already taking another any other medicine that contains sofosbuvir
• if you are on any medicines that contains cobicistat, elvitegravir, emtricitabine, tenofovir, carbamazepine, oxcarbazepine, phenobarbital, phenytoin, rifabutin, rifampin, rifapentine, rosuvastatin, simeprevir, St. John`s wort, tipranavir or ritonavir

Tell your doctor know if you:

• are pregnant, planning to become pregnant, or are breast-feeding
• are currently taking any prescription or non-prescription drugs, herbal preparations, or dietary supplements
• are allergic to any medicines, foods, or other substances
• have liver or kidney problems

If any of the above apply to you, you may still be able to take Ledifos, but should discuss the possibility of different treatment this with your doctor before beginning treatment.

Some medicines can interact negatively with Ledifos, or vice versa.

• Simeprevir because it may increase the risk of ledipasvir and sofosbuvir`s side effects
• Carbamazepine, oxcarbazepine, phenobarbital, phenytoin, rifabutin, rifampin, rifapentine, St. John`s wort, or tipranavir because they may decrease ledipasvir and sofosbuvir`s effectiveness
• Digoxin or rosuvastatin because the risk of their side effects may be increased by ledipasvir and sofosbuvir